Caroline McGregor is Vice President, Analytical Research & Development and has been in her current role since April 2018. In this role, she leads a group of managers & scientists committed to effective execution on the Merck pipeline from Discovery through filing and launch by delivering integrated physical, analytical and bioanalytical solutions and through application of innovative technologies while leveraging critical network collaborations, and interactions with the external scientific and regulatory communities. This includes all modalities, small molecules, biologics & vaccines.
Caroline’s career with Merck began in 2001 as a preformulation scientist in Pharmaceutical Sciences with a focus on bringing pharmaceutical sciences and drug delivery expertise to Discovery and Early Development. She led teams covering all aspects of physical characterization to support salt and polymorph selection as well as development of formulations which optimize exposure and duration of action for preclinical PK, efficacy and toxicology studies. She has held positions of increasing responsibility during her tenure. She was Director & Site Lead for Discovery Pharmaceutical Sciences in Boston for 5 years and was Executive Director Discovery Pharmaceutical Sciences for 2 years prior to moving to Process Research & Development in 2015. Initially the scope of this role was leading Analytical Chemistry with a focus on analytical development for small molecule active pharmaceutical ingredients which was then expanded her current scope in Analytical Research & Development.
Caroline was educated at the University of Strathclyde in Glasgow, Scotland, where she graduated in 1998 with a BSc in Chemistry. In 2001, she received her PhD in Chemistry from the University of Cambridge for a thesis which focused on design of novel liposomal drug delivery systems for DNA and small molecules. She is the author of various publications in the fields of characterization of pharmaceutical materials and drug delivery.