E19-02: Modern Mass Spectrometry: Fundamentals to Frontiers

Two-Day Course
E19-02, Sunday, Nov. 17 – Monday, Nov. 18; 8:30am – 5:00pm

Dr. Athula Attygalle, Stevens Institute of Technology, Hoboken, NJ

COURSE DESCRIPTION
This two-day course covers mass spectrometry fundamentals as well as the latest developments in the field, with emphasis on biological and biochemical applications. You will: learn strategic procedures followed by mass spectrometrists; improve the way you approach solving an analytical problem by mass spectrometry; learn about interfacing chromatographic procedures with mass spectrometry; and learn peripheral technologies required for mass spectrometry.

WHO SHOULD ATTEND
Novices who plan to find employment in analytical mass spectrometry, and practicing mass spectrometrists who intend to improve their skills.

TOPICS
1. Basics
a. Brief review of spectroscopic techniques
b. Overview of mass spectrometry
c. Mass spectrometric terms
2. Ion Detection
a. Detection of gaseous ions
3. Ion generation
a. Electron and chemical ionization
b. Electrospray and laser methods
c. APPI, DART, HePI, APCI, LAESI, MAI, LTTP, ASAP
4. Mass Analysis
a. Magnetic sector
b. Quadrupoles and ion traps
c. Time-of-flight
d. FTMS, Orbitrap
5. Data Acquisition, Elemental Composition, and Accurate Mass Determinations
6. Ion Activation and Tandem Mass Spectrometric Procedures
7. Quantification Methods and Application of Mass Spectrometric Methods for Environmental, Biological, Pharmacological, Forensic, and Geochemical Samples

ABOUT THE INSTRUCTOR
Dr. Athula B. Attygalle is a faculty member in the Department of Chemistry and Chemical Biology at Stevens Institute of Technology in Hoboken, New Jersey. Before joining Stevens, he served as the director of the mass spectrometry facility of Cornell University from 1988 to 2001. Dr. Attygalle is internationally recognized as a researcher and an educator for mass spectrometry and chemical ecology. Under Dr. Attygalle’s leadership, the mass spectrometry laboratory at Stevens Institute of Technology has become one of the leading centers for gas phase ion fragmentation studies. He has also published more than 200 peer-reviewed research articles. He has extensive experience in conducting workshops and lectures on mass spectrometry.  He has conducted mass spectrometry workshops in Malaysia, Pakistan, Brazil, Costa Rica, the Dominican Republic, Switzerland, Saudi Arabia, Germany and India.